Signs and symptoms:
a deeper look

  • Severe
    abdominal pain
  • Urine
  • Paresis
  • Convulsions
  • Neurologic
  • Mild sensory
  • Mental
Take the diagnostic challenge

Atypical presentations can occur. Conversely, not all symptoms in porphyric patients may be due to AIP. In addition, symptoms of AIP may vary considerably, even in the same patient during different episodes. 1,5,6

Watch the “Is It AIP?”
video to learn more
about AIP.


  1. Anderson KE, Bloomer JR, Bonkovsky HL, Kushner JP, Pierach CA, Pimstone NR, Desnick RJ. Recommendations for the diagnosis and treatment of the acute porphyrias. Ann Intern Med. 2005;142:439-450.
  2. Besur S, Hou W, Schmeltzer P, Bonkovsky HL. Clinically important features of porphyrin and heme metabolism and the porphyrias. Metabolites. 2014;4:977-1006.
  3. Ventura P, Cappellini MD, Biolcati G, Guida CC, Rocchi E. A challenging diagnosis for potential fatal diseases: Recommendations for diagnosing acute porphyrias. Eur J Intern Med. 2014;25:497-505.
  4. Ventura P, Cappellini MD, Rocchi E. The acute porphyrias: A diagnostic and therapeutic challenge in internal and emergency medicine. Intern Emerg Med. 2009;4:297-308.
  5. Gonzalez-Arriaza HL, Bostwick JM. Acute porphyrias: A case report and review. Am J Psych. 2003;160(3);450-458.
  6. Thadani H, Deacon A, Peters T. Diagnosis and management of porphyria. BMJ. 2000;320(7250);1647-1651.